Sangeetha, Krishnan , Bradley, Roach , Kanimozhi, Kasinathan , Panneerselvam, Annamalai , Thajuddin, Nooruddin , Gunasekaran, M .
Studies on the Biodegradation of Cephalosporin Drugs in Pharmaceutical Effluent using Pseudomonas putida and Pseudomonas fluorescence.
Environmental pollution caused by the release of a wide range of compounds into the environment as a consequence of industrial progress has now assumed serious problem of today's life. Over the last few decades, significant quantities of these chemicals have been released into the environment creating countless number of contaminated sites. In the present study, the waste water effluent was collected from a leading pharmaceutical industry, Chennai, at two different sites, the Aeropac digester and effluent tank. Two bacterial strains Pseudomonas putida and P.fluorescens were subjected to biodegradation of pharmaceutical effluent treatment. The physiochemical parameters such as COD, pH, TDS and electrical conductivity were monitored before and after biodegradation process. The biodegradation of effluent filtrate were analyzed for cefoxitin sodium, ceftiofur sodium and ceftriaxone sodium were measured by HPLC. Among the three antibiotics, Cefoxitin sodium was more degraded by P. putida (85%) than P. fluorescens (64%) and the mixture of the both strains followed by ceftiofur sodium (58%) and by the mixture of both strains (52%). Similarly ceftriaxone sodium was also more degraded at maximum amount by P.putida (60%) than P. fluorescens (52%) and by mixture of both strains (60%). All three antibiotic forms of cephalosporin degraded more effectively by P.putida than P. fluorescens or mixture of both strains. Hence P.putida is considered as highly potential antibiotic degrading bacterium which is an economic versatile, environment-friendly and efficient one.
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1 - Sri Pushpam College, Botany and Microbiology, Poondi, Tamilnadu, 613503, Tamilnadu
2 - Fisk University, Biology, 1000 17th Ave North, Nashville, , TN, 37208, USA
3 - Sri Pushpam College, , Botany and Microbiology, , Poondi, Tamilnadu, 613503,, India
4 - Sri Pushpam College, Botany and Microbiology, Poondi, 613503, Tamilnadu , India
5 - Bharathidasan University, Microbiology, Tiruchirappalli, Tamilnadu, 620240, India
6 - Fisk University, Biology, 1000 17th Ave North, Nashville, TN, 37208, USA
agro industrial wastes.
Presentation Type: Poster:Posters for Sections
Location: Battelle South/Convention Center
Date: Monday, July 9th, 2012
Time: 5:45 PM