Genomics / Proteomics
Hawkins, Kevin , Brown, Jennifer , McDermott, Ross , Moore, Richard .
The Role of Selection in Carica papaya Genomic Evolution.
Genomic evolution is the cornerstone of biodiversity, in that phenotypic diversity is based on the expression of the genotype. We investigated the relationship between levels of genomic diversity and recombination in autosomal regions of varying recombination frequency of the Carica papaya (papaya) genome. Analyses in other organisms suggest that recombination affects levels of genetic diversity by disrupting the footprint of selection on linked neutral diversity. As such, in regions of low recombination selection's footprint would larger, and linked neutral variation would be reduced due to hitchhiking. This study used 42 autosomal loci that were divided into 3 different recombination groups (low, average, and high recombination rate). The loci were amplified, sequenced, and polymorphic data were analyzed for diversity and divergence with comparison to the out-group, Jacaratia dolichaula. Preliminary analysis suggests that there is a positive correlation among the levels of diversity and recombination frequency in the papaya genome, and that this correlation is due to the enhanced affect of selection on linked neutral variation in regions of low recombination rather than any mutatgenic effects of recombination. The results from this study will be used to better understand the evolution sex chromosomes within papaya, which unlike many other sex chromosome systems, are limited to a pericentromeric region of chromosome 1.
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1 - Miami University, Botany, 316 Pearson Hall, Oxford, OH, 45056, USA
2 - Miami University, Botany, 316 Pearson, Oxford, OH, 45056, USA
Presentation Type: Poster:Posters for Topics
Location: Battelle South/Convention Center
Date: Monday, July 9th, 2012
Time: 5:30 PM